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Prothena Corporation NasdaqGS:PRTA Prothena Corporation plc, a late-stage clinical biotechnology company, focuses on discovery and development of novel therapies to treat diseases caused by protein dysregulation in the United States. Its product pipeline includes birtamimab, an investigational humanized antibody, which in phase 3 clinical trial to treat patients with AL amyloidosis; and Prasinezumab, an investigational humanized monoclonal antibody which is in phase 2b clinical trial, as well as phase 1 and 2 clinical trials for the treatment of parkinson's disease and other synucleinopathies. The company also develops Coramitug, an investigational antibody, which is in phase 2 clinical trial for potential treatment of transthyretin amyloidosis; BMS-986446, an investigational antibody, which is in phase 2 clinical trial to treat Alzheimer's disease; PRX012, an investigational antibody, which is in phase 1 clinical trial to treat Alzheimer's disease; PRX123, a Dual Aß-Tau Vaccine, which is in preclinical trial for treating Alzheimer's disease; and PRX019, an investigational antibody, which is in phase 1 clinical trial for the potential treatment of neurodegenerative diseases. It has a license, development, and commercialization agreement with F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. to develop and commercialize antibodies that target a-synuclein, including prasinezumab; and master collaboration agreement with Bristol Myers Squibb to develop and commercialize antibodies targeting tau, TDP-43. Prothena Corporation plc was incorporated in 2012 and is based in Dublin, Ireland.
Location: 77 Sir John Rogerson’s Quay, Dublin, D02 VK60, Ireland | Website: https://www.prothena.com | Industry: Biotechnology | Sector: Healthcare
Market Cap
NaN
52 Wk Range
$ - $
Previous Close
$N/A
Open
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Day Range
N/A - N/A
Volume
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Avg Volume
N/A
Enterprise Value
-21.25M
Cash
417.9M
Avg Qtr Burn
-32.59M
Short % of Float
19.49%
Insider Ownership
19.01%
Institutional Own.
88.72%
Qtr Updated
03/31/25
Drug Pipeline
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Drug & Indication | Stage & Event | Catalyst Date |
---|---|---|
Phase 3 Data readout | ||
BMS-986446 (PRX005) Details Alzheimer's disease | Phase 2 Data readout | |
Phase 2 Data readout | ||
Prasinezumab Details Neurodegenerative disease, Parkinson's disease | Phase 2 Update | |
PRX019 Details Neurodegenerative disease | Phase 1 Data readout | |
PRX012 Details Alzheimer's disease | Phase 1 Data readout | |
PRX123 Details Alzheimer's disease | Phase 1 Initiation |