Pyxis Oncology, Inc., a clinical stage company, engages in the development of therapeutics to treat solid tumors. Its lead antibody-drug conjugates (ADC) product candidate is PYX-201, an investigational novel ADC consisting of human immunoglobulin G1 (IgG1), which is in Phase 1 clinical trial to treat patients with relapsed or refractory solid tumors; and lead immuno-oncology (IO) product candidate is PYX-106, an investigational fully human IgG1 Siglec-15-targeting antibody that is in Phase 1 clinical trial to treat patients with advanced solid tumors. The company is also developing PYX-107, a CD40 agonist with demonstrated anti-cancer activity in patients with several cancer indications, which is in Phase 2 clinical trial for the treatment of tumors, such as soft tissue sarcomas, esophageal and gastroesophageal junction, cancers, and pancreatic ductal adenocarcinoma. It has in-license agreement with Pfizer Inc. to develop and commercialize ADC product candidates, including micvotabart pelidotin and PYX-203, and other ADC product candidates directed to the licensed targets; and Biosion USA, Inc. for development, manufacture, and commercialization of PYX-106, an IO product candidate. Pyxis Oncology, Inc. was incorporated in 2018 and is headquartered in Boston, Massachusetts. Show more
Location: 321 Harrison Avenue, Boston, MA, 02118, United States | Website: https://www.pyxisoncology.com | Industry: Biotechnology | Sector: Healthcare
Market Cap
71.86M
52 Wk Range
$0.83 - $5.39
Previous Close
$1.19
Open
$1.19
Volume
715,064
Day Range
$1.14 - $1.19
Enterprise Value
-17.45M
Cash
105.4M
Avg Qtr Burn
-14.87M
Insider Ownership
23.41%
Institutional Own.
38.25%
Qtr Updated
03/31/25
Drug Pipeline
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Drug & Indication | Stage & Event | Catalyst Date |
---|---|---|
Micvotabart pelidotin (MICVO, formerly PYX-201) + Pembrolizumab Details Solid tumor/s (various) | Phase 1/2 Data readout | |
Micvotabart pelidotin (MICVO, formerly PYX-201) Details Cancer, r/m Head and neck squamous cell carcinoma (HNSCC) 2/3L Platinum & PD-1 Experienced | Phase 1/2 Data readout | |
Micvotabart pelidotin (MICVO, formerly PYX-201) Details Cancer, r/m Head and neck squamous cell carcinoma (HNSCC) EGFRi & PD-1 Experienced | Phase 1/2 Update | |
Micvotabart pelidotin (MICVO, formerly PYX-201) Details Cancer, r/m Head and neck squamous cell carcinoma (HNSCC) 1/2L+ | Phase 1/2 Update | |
Micvotabart pelidotin (MICVO, formerly PYX-201) Details Head and neck cancer, Breast cancer, Thyroid cancer, Lung cancer | Phase 1 Data readout | |
PYX-106 Details Colorectal cancer , Kidney cancer, Bladder cancer, Cholangiocarcinoma | Failed Discontinued |