Summit Therapeutics Inc., a biopharmaceutical company, focuses on discovery, development, and commercialization of patient, physician, caregiver, and societal friendly medicinal therapies. Its lead development candidate is ivonescimab, a bispecific antibody for immunotherapy through blockade of PD-1 with the anti-angiogenesis, as well as in Phase III clinical trials for the treatment of non-small lung cancer. The company was founded in 2003 and is headquartered in Miami, Florida. Show more

601 Brickell Key Drive, Miami, FL, 33131, United States

Biotechnology
Healthcare
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Market Cap

11.98B

52 Wk Range

$13.83 - $36.91

Previous Close

$15.94

Open

$15.75

Volume

2,092,331

Day Range

$15.72 - $16.27

Enterprise Value

15.21B

Cash

238.6M

Avg Qtr Burn

-93.08M

Insider Ownership

86.05%

Institutional Own.

16.16%

Qtr Updated

09/30/25


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Drug & IndicationStage & EventCatalyst Date
Ivonescimab + chemotherapy Details
EGFR-mutated, advanced non-squamous NSCLC (2L+ EGFRm NSCLC)

PDUFA

Approval decision

Ivonescimab Details
1L PD-L1 positive Non-small cell lung carcinoma

Phase 3

Data readout

Phase 3

Data readout

Ivonescimab (SMT112) Details
1L Non-small cell lung carcinoma

Phase 3

Data readout

Ivonescimab + chemotherapy Details
EGFR-mutated, advanced non-squamous NSCLC

Phase 3

Update

Ivonescimab Details
PD-L1 positive NSCLC

Phase 3

Update

Phase 3

Update

Ivonescimab Details
Colorectal cancer (CRC)

Phase 3

Update

Ridinilazole Details
Intestinal infection, Bacterial infection

Failed

Discontinued