Summit Therapeutics Inc., a biopharmaceutical company, focuses on discovery, development, and commercialization of patient, physician, caregiver, and societal friendly medicinal therapies. Its lead development candidate is ivonescimab, a bispecific antibody for immunotherapy through blockade of PD-1 with the anti-angiogenesis for the treatment of non-small lung cancer (NSCLC) and colorectal cancer (CRC). The company has also combined ivonescimab with chemotherapy, which is in phase III clinical trial for the patients with epidermal growth factor receptor, mutated, and locally advanced or metastatic non-squamous NSCLC; first-line metastatic NSCLC; and first-line unresectable metastatic CRC. It markets its products in the United states, Canada, Europe, Japan, Latin America, Middle East, and Africa. The company was founded in 2003 and is headquartered in Miami, Florida. Show more

601 Brickell Key Drive, Miami, FL, 33131, United States

https://www.smmttx.com

Biotechnology

Healthcare

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Market Cap

10.92B

52 Wk Range

$12.55 - $30.98

Previous Close

$14.07

Open

$14.38

Volume

8,723,161

Day Range

$13.56 - $14.60

Enterprise Value

10.34B

Cash

598.7M

Avg Qtr Burn

-122.3M

Insider Ownership

83.14%

Institutional Own.

15.84%

Qtr Updated

03/31/26

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Drug & Indication	Stage & Event	Catalyst Date
Ivonescimab + chemotherapy Details EGFR-mutated, advanced non-squamous NSCLC (2L+ EGFRm NSCLC)	PDUFA Approval decision	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
Ivonescimab Details 1L PD-L1 positive Non-small cell lung carcinoma	Phase 3 Data readout	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
Ivonescimab (SMT112) Details 1L Non-small cell lung carcinoma	Phase 3 Data readout	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
Ivonescimab + chemotherapy Details EGFR-mutated, advanced non-squamous NSCLC	Phase 3 Update	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
Ivonescimab (SMT112) (PD-1 VEGF Bispecific) Details Recurrent/Metastatic Head And Neck Squamous Cell Carcinoma (PD-L1 Positive)	Phase 3 Update	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
Ivonescimab (SMT112/AK112) (PD-1/VEGF Bispecific) Details Recurrent/Metastatic PD-L1 Positive Head And Neck Squamous Cell Carcinoma	Phase 3 Update	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
Ivonescimab (SMT112) +Chemotherapy Details Biliary Tract Cancer	Phase 3 Update	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
Ivonescimab Details PD-L1 positive NSCLC	Phase 3 Update	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
Ivonescimab Details Colorectal cancer (CRC)	Phase 3 Update	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
Ivonescimab + Chemotherapy Details Squamous NSCLC	Phase 3 Update	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
Ivonescimab (AK112) (PD-1 VEGF Bispecific) Details First-Line Unresectable Metastatic Colorectal Cancer (MSS)	Phase 2 Update	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
Ivonescimab (AK112) (PD-1/VEGF Bispecific) Details First-Line Unresectable Microsatellite Stable Metastatic Colorectal Cancer	Phase 2 Update	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
Ridinilazole Details Intestinal infection, Bacterial infection	Failed Discontinued	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.