Celldex Therapeutics, Inc., a biopharmaceutical company, engages in developing therapeutic antibodies for patients with severe inflammatory, allergic, autoimmune, and other diseases. The company's drug candidates include monoclonal and bispecific antibodies designed to address mast cell mediated diseases for which available treatments are inadequate. Its clinical development programs are Barzolvolimab (CDX-0159), a monoclonal antibody that specifically binds the KIT receptor and potently inhibits its activity for treating chronic urticarias, prurigo nodularis, eosinophilic esophagitis, and atopic dermatitis; and CDX-622, a bispecific candidate for inflammatory diseases, which targets two complementary pathways that drive chronic inflammation, potently neutralizing the alarmin thymic stromal lymphopoietin and depleting mast cells through stem cell factor starvation. The company is headquartered in Hampton, New Jersey. Show more
Location: Perryville III Building, Hampton, NJ, 08827, United States | Website: https://www.celldex.com | Industry: Biotechnology | Sector: Healthcare
Market Cap
1.329B
52 Wk Range
$14.40 - $47.00
Previous Close
$20.01
Open
$20.24
Volume
1,883,571
Day Range
$20.19 - $23.88
Enterprise Value
701.5M
Cash
630.3M
Avg Qtr Burn
-46.55M
Insider Ownership
0.24%
Institutional Own.
-
Qtr Updated
06/30/25
Drug Pipeline
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Drug & Indication | Stage & Event | Catalyst Date |
---|---|---|
Barzolvolimab (CDX-0159) (KIT receptor) Details Chronic spontaneous urticaria | Phase 3 Data readout | |
Barzolvolimab (CDX-0159) Details Chronic inducible urticaria | Phase 3 Initiation | |
Barzolvolimab (CDX-0159) (KIT receptor) Details Prurigo nodularis, Skin disease/disorder | Phase 2 Data readout | |
Barzolvolimab (CDX-0159) (KIT receptor) Details Atopic dermatitis | Phase 2 Data readout | |
Phase 2 Data readout | ||
CDX-585 Details Solid tumor/s, Cancer | Phase 1 Data readout | |
CDX-622 Details Inflammatory disease | Phase 1 Data readout | |
CDX-527 (and PD-L1 / CD27) Details Solid tumor/s, Cancer | Failed Discontinued | |
CDX-1140 (CD40 agonist) Details Solid tumor/s, Cancer, Diffuse large B cell lymphoma | Failed Discontinued |