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Cogent Biosciences Inc NASDAQ:COGT Cogent Biosciences is a biotechnology company focused on developing precision therapies for genetically defined diseases. The most advanced clinical program, PLX9486, is a selective tyrosine kinase inhibitor that is designed to potently inhibit the KIT D816V mutation as well as other mutations in KIT exon 17. KIT D816V is responsible for driving systemic mastocytosis, a serious disease caused by unchecked proliferation of mast cells. Exon 17 mutations are also found in patients with advanced gastrointestinal stromal tumors (GIST), a type of cancer with strong dependence on oncogenic KIT signaling. Cogent Biosciences is headquartered in Cambridge, MA.

Location: | Website: www.cogentbio.com | Industry: Pharmaceutical Preparation Manufacturing | Sector: Manufacturing

Market Cap

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52 Wk Range

$ - $

Previous Close

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Day Range

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Volume

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Avg Volume

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Enterprise Value

368.3M

Cash

287.1M

Avg Qtr Burn

-51.95M

Short % of Float

16.92%

Insider Ownership

0.16%

Institutional Own.

Qtr Updated

12/31/24

Drug Pipeline

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Drug & Indication	Stage & Event	Catalyst Date
Bezuclastinib (CGT9486) (KIT exon 17 inhibitor) + Sunitinib Details Cancer, Gastrointestinal stromal tumors	Phase 3 Data readout	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
Bezuclastinib (CGT9486) (KIT exon 17 inhibitor) Details Advanced systemic mastocytosis (AdvSM)	Phase 2 Data readout	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
Bezuclastinib (CGT9486) (KIT exon 17 inhibitor) Details Nonadvanced systemic mastocytosis	Phase 2 Data readout	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
CGT4859 (FGFR2 inhibitor) Details Advanced cholangiocarcinoma	Phase 1 Data readout	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
CGT4255 / CNS-penetrant ErbB2 program Details Solid tumor/s	IND Submission	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.