Fulcrum Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops small molecules to improve the lives of patients with genetically defined diseases in the areas of high unmet medical need in the United States. Its clinical-stage product candidate is pociredir, a fetal hemoglobin inducer, which is in phase 1b clinical trial for the treatment of sickle cell disease and beta-thalassemia. The company also discovers programs for the treatment of diamond-blackfan anemia, Bone Marrow Failure Syndromes, novel fetal hemoglobin inducers, fibrotic disorders. It has licensce agreement with CAMP4 which includes certain small molecule compounds, composition of matter and method of use patent rights, and know-how to research, develop, manufacture, use, and commercialize. Fulcrum Therapeutics, Inc. was Incorporated in 2015 and is headquartered in Cambridge, Massachusetts. Show more
26 Landsdowne Street, Cambridge, MA, 02139, United States
Market Cap
448.2M
52 Wk Range
$2.31 - $15.74
Previous Close
$6.94
Open
$6.93
Volume
390,887
Day Range
$6.68 - $7.00
Enterprise Value
107M
Cash
352.3M
Avg Qtr Burn
-16.8M
Insider Ownership
3.86%
Institutional Own.
-
Qtr Updated
12/31/25
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| Drug & Indication | Stage & Event | Catalyst Date |
|---|---|---|
Pociredir (FTX-6058) Details Sickle cell disease | Phase 1b Update | |
Losmapimod Details Muscle degeneration, Muscle weakness, Facioscapulohumeral muscular dystrophy | Failed Discontinued | |
Losmapimod Details COVID-19 | Failed Discontinued |
