OPKO Health, Inc. operates as a healthcare company, in the United States, Ireland, Chile, Spain, Israel, Mexico, and internationally. The company operates in two segments, Pharmaceutical and Diagnostics. The Pharmaceutical segment develops MDX2001, a tetra-specific antibody targeting several types of solid tumors in Phase 1 clinical trials; MDX2003, a tetra-specific antibody targeting two antigens for hematological tumors in Phase 1 clinical trials; and MDX2004, a trispecific immune modulator to rebuild and sustain the patient's own immune system. This segment also engages in the development of Epstein Barr Virus vaccine; Rayaldee, a patented extended-release product for oral administration containing 30 mcg of a prohormone; OPK-88006 oral and injectable product to regulate blood glucose and reduce body weight; NGENLA, recombinant human growth hormone product developed for the long-term treatment of pediatric patients with growth hormone deficiency. The Diagnostics segment offers laboratory testing services, such as detection, diagnosis, evaluation, monitoring, and treatment of diseases, as well as esoteric testing, molecular diagnostics, anatomical pathology, genetics, women's health, and correctional healthcare under the BioReference brand; and 4Kscore test. OPKO Health, Inc. was founded in 2006 and is headquartered in Miami, Florida. Show more
4400 Biscayne Boulevard, Miami, FL, 33137, United States
Market Cap
913.6M
52 Wk Range
$1.11 - $1.87
Previous Close
$1.19
Open
$1.20
Volume
2,357,280
Day Range
$1.18 - $1.22
Enterprise Value
931M
Cash
369.1M
Avg Qtr Burn
-25.92M
Insider Ownership
49.26%
Institutional Own.
26.87%
Qtr Updated
12/31/25
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| Drug & Indication | Stage & Event | Catalyst Date |
|---|---|---|
Rayaldee (calcifediol ER capsules) Details Chronic kidney disease | Approved Quarterly sales | |
NGENLA® Somatrogon Details Pediatric growth hormone deficiency | Approved Quarterly sales | |
OPK88003 (oxyntomodulin analog) (GLP-1R/GCGR agonist) Details Type 2 diabetes | Phase 2 Update | |
MDX2004 Details Advanced cancers | Phase 1/2 Update | |
MDX2001 (Tetraspecific LASER) Details Cancer, Solid tumor/s | Phase 1b Initiation | |
MDX2201 Details Epstein-Barr virus, Vaccine | Phase 1 Data readout | |
SAR441236 Details Human immunodeficiency virus | Phase 1 Update | |
MDX2301 (Tetravalent Bispecific Antibody) Details COVID-19 Infection | Phase 1 Initiation | |
MDX2003 (Trispecific T-Cell Engager) Details Leukemia And Lymphoma | Phase 1 Initiation | |
Rayaldee Details COVID-19 | Failed Discontinued |
