ProQR Therapeutics N.V., a clinical-stage biotechnology company, focuses on the discovery and development of novel therapeutic medicines. The company develops an RNA editing platform through its Axiomer RNA editing technology for genetic disorders with unmet needs. Its lead product candidate, AX-0810, targets na-taurocholate cotransporting polypeptide (NTCP) for the treatment of cholestatic diseases. The company also develops AX-2402, which targets methyl CpG binding protein 2 mutations for Rett syndrome; AX-2911, which targets PNPLA3 for metabolic dysfunction-associated steatohepatitis; and AX-1412, which targets the B4GALT1 gene for cardiovascular diseases. It has a research and collaboration agreement with Eli Lilly and Company for the discovery, development, and commercialization of potential new medicines for genetic disorders in the liver and nervous system. The company was incorporated in 2012 and is headquartered in Leiden, the Netherlands. Show more
Zernikedreef 9, Leiden, 2333 CK, Netherlands
Market Cap
191.7M
52 Wk Range
$1.07 - $3.10
Previous Close
$1.82
Open
$1.84
Volume
458,642
Day Range
$1.70 - $1.84
Enterprise Value
87.59M
Cash
106.9M
Avg Qtr Burn
-12.24M
Insider Ownership
18.10%
Institutional Own.
50.80%
Qtr Updated
09/30/25
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| Drug & Indication | Stage & Event | Catalyst Date |
|---|---|---|
AX-0810 Details NTCP for Cholestatic diseases | Phase 1 Data readout | |
AX-2911 (RNA Editing Oligonucleotide) Details Metabolic-Associated Steatohepatitis (PNPLA3 I148M) | Phase 1 Initiation | |
AX-2402 (RNA Editing Oligonucleotide) Details Rett Syndrome (MECP2 R270X) | Phase 1 Initiation | |
QR-1123 (RNase H mediated cleavage) Details Mediated retinitis pigmentosa, Rho mediated retinitis pigmentosa | Failed Discontinued | |
Ultevursen (QR-421a) (Exon 13) Details Mediated retinitis pigmentosa, Usher syndrome, Heart disease, Heart failure | Failed Discontinued | |
Sepofarsen (QR-110) (CEP290 gene) Details Leber congenital amaurosis, Eye disease , Genetic disorder | Failed Discontinued | |
QR-504a Details Genetic disorder, Eye disease , Leber congenital amaurosis | Failed Discontinued |
